University of California San Francisco

Biography

Chris E. Freise, M.D. received his medical degree from the University of Minnesota where he also did his internship and residency in General Surgery. He later completed a  transplantation fellowship at UCSF.   

He is a member of numerous professional organizations including The Transplantation Society, the International Pancreas and Islet Transplant Association, the Transplant Infectious Disease Society, the American Hepato-Pancreato-Billiary Association and the Society of University Surgeons. In addition, he recently served as the Medical Director for California Transplant Donor Network. He is also the Associate Counselor for UNOS Region 5, and a member of the UNOS Membership and Professional Standards Committee.

Dr. Freise has authored more than eighty (80) in peer-reviewed publications and five (5) book chapters. He is an accomplished researcher and clinical educator. Dr. Freise is also a frequent invited lecturer to national and international and conferences in the field.         

Education

Institution Degree Dept or School End Date
University of California Diversity, Equity, and Inclusion Champion Training 2019
University of California, San Francisco Transplant Fellowship School of Medicine 1995
University of California, San Francisco Post-Doc Fellow/Scholar School of Medicine 1991
University of Minnesota M.D. School of Medicine 1986

Board Certifications

  • American Board of Surgery, 1995

Clinical Expertise

Bile Duct Injuries
Bile Duct Strictures
Cholangiocarcinoma (Bile Duct Cancer)
Choledochal Cyst Disease
Dialysis Access
Expanded Criteria Donor Kidney Transplantation
Fulminant Hepatic Failure
Hepatitis B
Hepatitis C
Hepatocellular Carcinoma (Liver Cancer)
Intestinal Transplantation and Rehabilitation
Kidney and LIver Transplantation in HIV Patients
Kidney Auto-transplantation
Kidney Transplantation
Laparoscopic Donor Nephrectomy
Laparoscopic Kidney and Liver Surgery
Liver Transplantation
Living Donor Kidney Transplantation
Living Donor Liver Transplantation
Pancreas Transplantation
Pediatric Kidney Transplantation
Pediatric Liver Transplantation
Polycystic Kidney Disease
Polycystic Liver Disease
Portal Hypertension
Surgical Shunts

Grants and Funding

  • Living Donor Liver Transplant :Short & Long-Term Impact on Donors and Recipients | NIH | 2002-09-01 - 2015-08-31 | Role: Principal Investigator

Research Narrative

Dr. Friese's basic science research focuses on the delivery of immunosuppressive agents to organ allografts, ischemia reperfusion injury, and methods to improve organ function in deceased donors. His clinical research includes  a multicenter trial investigating donor and recipient outcomes following living donor liver transplantation.

Research Interests

Delivery of Immunosuppressive Agents to Organ Allografts

Ischemia Reperfusion Injury

Improvement Organ Function in Deceased Donors

Publications

MOST RECENT PUBLICATIONS FROM A TOTAL OF 125
  1. Increased efficacy of CSA following rearterialization in the rat OLTX model.
    Freise CE, Liu T, Osorio RW, Ferrell L, Ascher NL, Roberts JP| | PubMed
  2. The increased efficacy and decreased nephrotoxicity of a cyclosporine liposome.
    Freise CE, Liu T, Hong K, Osorio RW, Papahadjopoulos D, Ferrell L, Ascher NL, Roberts JP| | PubMed
  3. Major histocompatibility complex class I deficiency prolongs islet allograft survival.
    Osorio RW, Ascher NL, Jaenisch R, Freise CE, Roberts JP, Stock PG| | PubMed
  4. Nonoperative management of biliary leaks after orthotopic liver transplantation.
    Osorio RW, Freise CE, Stock PG, Lake JR, Laberge JM, Gordon RL, Ring EJ, Ascher NL, Roberts JP| | PubMed
  5. Maintenance immunosuppression with prednisone and RS-61443 alone following liver transplantation.
    Freise CE, Hebert M, Osorio RW, Nikolai B, Lake JR, Kauffman RS, Ascher NL, Roberts JP| | PubMed
  6. Isolation of functional MHC class I-deficient islet cells.
    Osorio RW, Ascher NL, Jaenisch R, Natuzzi ES, Freise CE, Roberts JP, Stock PG| | PubMed
  7. Orthotopic liver transplantation for end-stage alcoholic liver disease.
    Osorio RW, Freise CE, Ascher NL, Roberts JP, Avery M, Lake JR| | PubMed
  8. Acute liver rejection: evaluation with cell-directed MR contrast agents in a rat transplantation model.
    Mühler A, Freise CE, Kuwatsuru R, Rosenau W, Liu T, Mintorovitch J, Clement O, Vexler V, Mahboubi S, Lang P| | PubMed
  9. A modified vascular "sleeve" anastomosis for rearterialization in orthotopic liver transplantation in rats.
    Liu T, Freise CE, Ferrell L, Ascher NL, Roberts JP| | PubMed
  10. Similar clinical presentation of neurotoxicity following FK 506 and cyclosporine in a liver transplant recipient.
    Freise CE, Rowley H, Lake J, Hebert M, Ascher NL, Roberts JP| | PubMed